RBC & Blood Platelets

 RBC :-

# Average life span of RBC = 120 days because of lacking of nucleus

# Erythropoises = formation of RBS & it is control by feedback mechanism , by erythropoitein (glycoprotein) secreted by kidney
# "Haemorrhage = loss of blood (bleeding)
- Mechanism when "Haemorrhage occur 

Loss of blood > Decrease supply of oxygen in tissue > stimulate the secretion of erythropoitein by kidney > erythropoieses ( formation of blood cell) > increase number of blood in tissue > More oxygen goes to tissue

# Formation of blood in featous happening in yolk sac , and it grow liver form blood, then in fully developed animal blood formation ocur in bone marrow

# Function of blood :-

- 97-99% of total oxygen are transpoted by blood to various parts of body as in form of oxyhaemoglobin
- about 23% of CO2 transported by blood in form of carboxylic haemoglobin
- pH of body also maintain by RBC & act as buffer solution

@ Leucocytes :- (WBC) 

there number is less than WBC , it around 1:600 to the ration of RBC & WBC
- T.L.C = total leucocyte count :- total number of leucocytes per micro litre of blood
- D.L.C = differential Leucocyte Count :- Realtive percentage of Blood
_ Haemocytometer :- For count RBC
- Haemoglobunator :- For count Hb (haemoglobin in blood)

# W.B.C Type :-

i) Granulocytes :-

these having granule
these are mainly of three type :-

~ Acidophile:-

 these are those granulocyte which attain acid strain & having 2 lobe

~ Basidiophile :-

 these are those granulocyte which attain basic strain & having 3 lobe

~ Neutrophile :-

 these are those granulocyte which attain no strain & having many lobe & having polymorphic nucleus

ii) Agranulocytes :-

these are those granule which doesnot having granules , mainly of two type

- Monocytes :- 

their size are small , & sometime monocytes get converted into macrocytes having large amount of lysosomes,
they are about 3-5% & having process called diapedsis (in which fluid come from vesicle & kill bacteria)

- Lymphocytes :-

They are about 30%

- Lymphocytes :-
These having big size than monocytes

@ Blood Platelets :-

* If 40,000 /µl Having Critical level of platelets
- Normal Platelets number 2.5-3.5 >< 10⁵ / cubic meter 

- Kiwi fruit increase number of platelets

- They are Non-nucleated
-They are smallest corpuscles of blood , having 2-4 µm
- These Having Granule , having 3 type Of Granule are
* α- Granule & Chemical release is platelet growth factor (PGF) & Thromboplastin * Dense Granule :- Release Chemical ATP & Serotonin

* Glycogen Granule :-

Release Chemical Glycogen
- If Platelets decreases below One Lakh / 1µl of Blood Called Thromocytopenia
- If Platelets Increases than 1 Lakh / 1µl of Blood Called Thromocytosis
- Life Span Of Blood Platelets 7-10 Day
- Per Day 30,000 Platelets are found 1µl of Blood

@ Blood Coagulation :-

Converting of Blood fluid from Gel Form to Prevent Further Blood Loss From Body During any Cut or injury
~ Time Estimate of Blood Coagulate = 30-60 Sec