TEST TUBE BABY

TEST TUBE BABY :-

The technique in in-vitro fertilization and in–vitro development followed by the embryo transfer in the uterus of the normal female to start the development and finally leading to normal birth, is called test tube baby

History :-

• First attempt was made by Italian scientist , Dr. Petrucci (1959 AD.) although these human embryo survive only 29 days,
• Robert Edwards was awarded the 2010 Nobel Prize in Physiology or Medicine "for the development of in-vitro fertilization"
• Then first test tube was born to Lesley & Gilbert Brown on july 25, 1978. In Oldham , England.
• The World first test tube baby was (a girl)  named as  louise Joy brown
• India’s first test tube baby was born on  3^rd October,1978 in Kolkata, her name was Kanupriya aggarwal and was created by Dr. Subhash Mukherjee.

 Procedure :-

a.)   Removal of unfertilized ovum fom reproductive tract of female

b.)   Ovum is kept under aseptic condition

c.)   Fusion of sperm to ovum in a culture medium , outside the female body , to form the zygote

d.)   Zygote is stimulated to Develop in vitro upto 32-celled stage

e.)   Developing embryo is implanted on the endometrium of the uterus at 32 celled stage . so the pregnancy in the women starts further development of the child continous in the womb till it is born

Baby produced by These method is called Test Tube baby

Significance :-

It is boon to infertile women

It can be used for men with oligospermia (low Sperm count)

Old Superior cow can donate Oocyte

Embryo can be frozen & preserved in an embryo tank for 10 years for future use