Enzyme

Enzyme :-

        these are those which are enhance the rate of process or rexn

@ Defination :-

           Enzyme are water soluble, colloidal organic macromolecules which are wholly or patially proteinaceous in nature, biological in origin, produced in microamounts and capable of catalyzing specific biochemical reactions under specific conditions , temperature and pH

@ History :-

 i) Brazelius, 1837 = he tells living cell produce ferment
ii) Louis pasteur , 1860 = Fermentation cause by specific enzyme of yeast
iii) W. Kuhne, 1878 =  He describe 1st presence of enzyme
iv) Edward Buchner ,1897 = He isolate first enzyme (zymase) , and gave term "Enzyme"
v) J.B Sumner ,1926 = he describe enzyme is proteinious in nature
- He isolate urese enzyme from jack bean
vi) Northrop ,1930-36 = He isolate many enzyme like tripsin etc further

# At Now we have about 2,000 enzyme on study

@ Enzyme do Reaction in controlled manner , act on otpimum temperature
@ Enzyme act as bio catalyst
@ Enzyme absence cause disease 9896199667 like Hexose ammunidex cause tay sach's disease
@ With agening enzyme also degraded

# Chemical nature :-

          - Enzyme may be Proteinious like pancreatic, RNAase, Protease
- Enzyme are form compound ptoteinious enzyme form by two parts

 i) Apoenzyme :-

               proteinious part of enzyme

ii) Prosthatic group :-

            non proteinious part may be co-enzyme or co-factor ex :- thymine
# Both part combined form holoenzyme